The aim is to provide corresponding quality of service (QoS) guarantee for real-time video data transmission. To ensure the high quality and smooth playback of video sequence at the receiving end, the design of multimedia transmission is made. In view of the shortcomings of selective frame loss, this paper adopts the active frame loss algorithm, which discards the nonkey frames according to the probability. With the increase of the frame loss rate at the transmitter, the proportion of decoded frames increases rapidly and reaches the maximum when the frame loss rate is 0.1. It is proved that active frame loss can control the bit rate more accurately to make full use of bandwidth resources and avoid the waste of bandwidth resources.