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Background. Although there have been many studies on the risk factors for coronary artery disease, the etiology of coronary artery spasm has not yet been determined.Methods and Results. After diagnosis by coronary arteriography, various risk factors were compared between two groups of subjects using logistic regression analysis. The vasospasm group included 175

Determination of the genotypes of the connexin 37, plasminogen-activator inhibitor type 1, and stromelysin-1 genes may prove reliable in predicting the genetic risk of myocardial infarction and might thus contribute to the primary prevention of this condition.

Probucol administered beginning 4 weeks before PTCA appears to reduce restenosis rates.

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