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ChemInform Abstract The oxazinium salt (I) reacts with 4-aminophenol (II) to give the 1-(4-hydroxyphenyl)pyrimidinium salt (III). Starting with the N-acetylacetoacetic amide (IV), the corresponding O-acetylated derivative (VIII) is prepared via the pyrimidones (V) and (VII). The analogous 2-and 3-hydroxyphenyl compounds are synthesized in the same manner. Coupling of acetobromoglucose (IX) with (V) leads to the formation of the glucoside (X). The compounds synthesized, especially the 4-hydroxyphenyl derivatives, have tranquilizing, neuroleptic, and antidepressive activity.

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