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The "He(p, 2p) H reaction has been studied at 250, 350, and 500 MeV using coplanar symmetric and asymmetric geometries. The data are presented as energy-sharing spectra, coplanar symmetric angular distributions, and quasifree angular distributions. A comparison with distorted wave impulse approximation calculations indicates reasonable agreement for small recoil momenta (q & 150 MeV jc). For larger recoil momenta, the distorted-wave impulse approximation calculations increasingly underestimate the data.The discrepancies are substantially reduced by inclusion of a spin-orbit term in the optical potential used to generate the distorted waves. Improvements of the single particle wave function for the struck nucleon influence the calculations to a lesser degree. The remaining discrepancies at large recoil momenta may, in part, be ascribed to multiple scattering effects and exchange processes not included in the standard distorted-wave impulse approximation.NUCLEAR REACTIONS He(p, 2p ) H; measured d~/(d Q3d Q~dT3), 250, 350, 500 MeV, energy sharing spectra, coplanar symmetric angular distributions, quasifree angular distributions; comparison with DWIA calculations.