doctor of chemistry, professor, academician of NAS RK, president of NAS RK, general director of JSC "Institute of fuel, catalysis and electrochemistry named after D.V. Sokolsky (Almaty, Kazakhstan) H = 4 Editorial board: ADEKENOV Sergazy Mynzhasarovich (deputy editor-in-chief) doctor of chemical sciences, professor, academician of NAS RK, director of the international Scientific and production holding «Phytochemistry» (Karaganda, Kazakhstan) H = 11 AGABEKOV Vladimir Enokovich (deputy editor-in-chief), doctor of chemistry, professor, academician of NAS of Belarus, honorary director of the Institute of Chemistry of new materials (Minsk, Belarus) H = 13 STRNAD Miroslav, head of the laboratory of the institute of Experimental Botany of the Czech academy of sciences, professor (Olomouc, Czech Republic) H = 66 BURKITBAYEV Mukhambetkali, doctor of chemistry, professor, academician of NAS RK, first vice-rector of al-Farabi KazNU (Almaty, Kazakhstan) H = 11 HOHMANN Judith, head of the department of pharmacognosy, faculty of Pharmacy, university of Szeged, director of the interdisciplinary center for Life sciences (Szeged, ungary) H = 38 ROSS Samir, Ph.D, professor, school of Pharmacy, national center for scientific research of Herbal Products, University of Mississippi (Oxford, USA) H = 35 KHUTORYANSKY Vitaly, Ph.D, pharmacist, professor at the University of Reading (Reading, England) H = 40 TELTAYEV Bagdat Burkhanbayuly, doctor of technical sciences, professor, corresponding member of NAS RK, ministry of Industry and infrastructure development of the Republic of Kazakhstan (Almaty, Kazakhstan) H = 13 PHARUK Asana Dar, professor at Hamdard al-Majid college of Oriental medicine. faculty of Oriental medicine, Hamdard university (Karachi, Pakistan) H = 21 FAZYLOV Serik Drakhmetovich, doctor of chemistry, professor, academician of NAS RK, deputy director for institute of Organic synthesis and coal chemistry (Karaganda, Kazakhstan) H = 6 ZHOROBEKOVA Sharipa Zhorobekovna, doctor of chemistry, professor, academician of NAS of Kyrgyzstan, Institute of Chemistry and chemical technology of NAS KR (Bishkek, Kyrgyzstan) H = 4 KHALIKOV Jurabay Khalikovich, doctor of chemistry, professor, academician of the academy of sciences of tajikistan, institute of Chemistry named after V.I. Nikitin AS RT (Tajikistan) H = 6 FARZALIEV Vagif Medzhid ogly, doctor of chemistry, professor, academician of NAS of Azerbaijan (Azerbaijan) H = 13 GARELIK Hemda, PhD in chemistry, president of the department of Chemistry and Environment of the International Union of Pure and Applied Chemistry (London, England) H = 15 News of the National Academy of Sciences of the Republic of Kazakhstan. Series of chemistry and technology.

One of the main tasks of organic chemistry is development of purposeful synthesis ways of biologically active substances. The chemistry of dithiocarbamic compounds opens up wide possibilities for solving this problem. There is a strong interest in dithiocarbamic acids due to a wide range oftheir biological activity (anticancer, antibacterial, antifungal, anti-neurodegenerative, anti-tuberculosis, growthstimulating, root forming, etc.). The purpose of this studyis the synthesis of biologically active substances inthe series of element(N-,O-,S-,F-,Cl-)organic compounds based on N-benzylmethylamine and indoline, their structure determination and biological activity investigation. Results and discussion. The initial sodium dithiocarbamates were synthesized by the reaction of N-benzylmethylamine and indoline with carbon disulfide in the yields 92 and 52%. Acylation of synthesized dithiocarbamates with acid chlorides was carried out and the corresponding derivatives of dithiocarbamic aromatic and heterocyclic thioanhydrides were obtained in the yields 58-85%. The structure of the synthesized compounds was identified by using elemental analysis, IR spectra, 1Н and 13С NMR spectroscopy. Laboratory study of growth-stimulating activity of new biologically active compounds onlaboratory germination and germination energy of wheat and soybean seeds was carried out.Conclusion.The best results were achieved when wheat seeds were treated with sodium indoline-1-carbodithioate and benzyl(methyl)carbamothio-4-fluorobenzoic thioanhydride at 0.001% concentration.Germination energy and laboratory seed germination were 100% and 100%, and for the standard -80% and 90%, respectively. It was found that seed treatment with new synthesized preparations intensively stimulates the growing and germination of wheat shoots in comparison with the control and the standard.