OBJECTIVES Prognosis for patients with non-small-cell lung cancer (NSCLC) who, after neoadjuvant/induction and surgery, have a pathological complete response (pCR) is expected to be improved. However, the place of the pCR patients in the context of the tumour, lymph node and metastasis (TNM) staging system is still not defined. The aim of this study is to investigate the long-term survival of NSCLC patients with pCR and to find their appropriate staging category within the TNM staging system. METHODS We retrospectively reviewed the prospectively recorded data of 1076 patients undergoing surgery (segmentectomy or more) for NSCLC between 1996 and 2016. Patients were divided into 2 groups. Group 1: clinical early-stage patients who underwent direct surgical resection (n = 660); group 2: patients who received neoadjuvant/induction treatment before surgical resection for locally advanced NSCLC (n = 416). Morbidity, mortality, survival rates and prognostic factors were analysed and compared. RESULTS Postoperative histopathological evaluation revealed pCR in 72 (17%) patients in group 2. Overall 5-year survival was 58.7% (group 1 = 62.3%, group 2 = 52.8%, P = 0.001). Of note, 5-year survival was 72.2% for pCRs. In addition, 5-year survival for stage 1a disease was 82.6% in group 1 and 63.2% in group 2 (P = 0.008); 70.3% in group 1 and 60.5% in group 2 for stage 1b (P = 0.08). Patients with stage II had a 5-year survival of 53.9% in group 1 and 51.1% in group 2 (P = 0.36). CONCLUSIONS This study shows that patients with locally advanced NSCLC developing a pCR after neoadjuvant/induction treatment have the best long-term survival and survival similar that of to stage Ib patients.

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The purpose of this study is to examine the contribution of sport to obese youth duringsocialization, considering the socio-cultural and economic characteristics of obese adolescents. In the study participated 118 obese children members of Ankara Metropolitan Municipality Family Life and Youth Centers who played sports or participated in sport activities in the 15-18 age range. As a data collection tool, the socialization scale consisting of 69 questions developed by Sahan (2007) was used. A computer-aided data analysis program was used in the research data. Frequency analysis was applied first and tables were made during the analysis of the data. The percentages of the variables in the sample were determined, and the characteristics of the sample were evaluated generally in these tables. Analysis procedures were applied according to hypotheses later. The data were evaluated by the Scheffe test, the Mann Whitney U test and the Kruskal-Wallis Nonparametric test. As a result of the research; it was found that there was no significant difference between the levels of socialization of obese youth according to the age variable and there was a significant difference between sexes, household income levels and the sports and socialization levels of obese youth who are interested and who are uninterested in sport. At the end of the research, it was observed that male obese teenagers had higher levels of socialization than female obese teenagers in terms of high income level and interest in sport.

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GirişAkciğer kanseri tüm dünyada olduğu gibi yurdumuzda da en sık görülen kanser çeşidi olup vakaların %90'ında etiyolojide sigara bulunmaktadır. Sigara tüm akciğer kanser alt tiplerinde etiyolojide yer almakla birlikte en güçlü ilişki küçük hücreli ve skuamöz hücreli akciğer kanserlerinde izlenmektedir (1). Yalnız akciğer kanserlerine spesifik olarak kabul edilebilecek herhangi bir belirti bulunmamakta birlikte hastaların çoğunda öksürük, balgam, hemoptizi ve nefes darlığı görülmektedir. Diğer taraftan halsizlik, iştahsızlık ve kilo kaybı gibi sistemik belirtiler de görülebilmektedir (2). Alt tiplere göre değişkenlik göstermekle birlikte akciğer kanserleri özellikle tanıda gecikilen vakalarda sıklıkla metastatiktir. Bu bağlamda hastalarda metastazlara bağlı belirtilerle de karşılaşılabilmektedir. Lokal metastazlar dışında kemik, karaciğer ve beyin en sık metastaz yaptıkları organlardır (3).