The leaves and roots of Rumex confertus Willd were tested in vitro for antibacterial and fungal activity in the fractions of gasoline, chloroform, ethyl acetate and butanol. As a result, it was found that the leaves of the Rumex confertus Willd plant, chloroform and ethyl acetate fractions of the root part have antibacterial activity against fungi and gram-positive bacteria. Keywords: Rumex confertus Willd, fractions, extracts, antibacterial, antifungal

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The aim of the present study to clarify the phytochemical constituents of Rumex plants, extraction, separation and structural identification of chemical components, provide theoretical support and scientific basis for its traditional use, further expand the application scope of traditional medicinal plant resources in Uzbekistan, and develop its potential value. Three known anthraquinone derivatives has been isolated from the chloroform fraction extract of Rumex pamiricus roots and two known compounds were separated from the ethyl acetate fraction extract of Rumex conglomeratus roots. Their structures were elucidated by extensive spectroscopic evidence and chemical methods. Qualitative analyses of major phenolics by TLC analysis were also evaluated. The ester oil from the aerial parts of Rumex confertus and Rumex pamiricus, the gasoline, chloroform, ethyl acetate and butanol extracts of Rumex pamiricus aerial part and alcohol extract of Rumex pamiricus roots were tested in vitro for antimicrobial activity. This study aimed to determine the in vitro antimicrobial activity of the medicinal plants traditionally used in Uzbekistan against the microbial strains associated with infectious diseases.