We assessed the influence of increasing stimulus intensity from motor threshold to pain threshold on short latency somatosensory evoked potentials recorded over the parietal and frontal scalp in 14 subjects during median nerve stimulation at the wrist. We used the curvature polynomial coefficient to evaluate alterations of the main components. The N20 and P27 curvature coefficients are not modified. The change of the N30 curvature coefficient is the result of shortened P45 latency. The increase of N60 curvature coefficient shows a great interindividual variability, probably due to a central amplification and synchronization or to involvement of nerve fibres with different excitability.
Autoregressive filtering has been applied to the detection of sleep spindles during polysomnography. This method has been reliable in infants and will help to the maturation studies in infants and children.
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