No abstract

Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg.

The article presents data concerning prevalence of sarmidosis in Tomsk and the Tomsk region for 16 years and impacting of ecological and geochemical factors (elemental composite of incrustation of snow, soils) on disease. The sarmidosis morbidity of individuals without undergoing impact of occupational hazards is reliably higher in areas with increased anthropogenic loading (the Oktiabrskii district of Tomsk, the Tomsk rural district, the North- Eastern sector, city of Seversk, Parabelskii and Kolpashevskii districts, Strejevoii). The positive associations were established between sarmidosis morbidity and content of sodium in incrustation of snow, cerium in soil. The sarmidosis with severe recurrent course correlated positively with lutetium and chrome of soils and negatively with barium in incrustation of snow.

No abstract

No abstract