Reflux after oesophagectomy is a significant problem, with both clinical and pathological consequences. Simple measures to facilitate gastric emptying, such as creating a gastric tube, performing a pyloric drainage procedure and using gastric motility agents, may produce a reduction in symptoms but do not alone control reflux itself. A variety of surgical reconstructions have been used, many of which are either difficult to fashion or not suitable when a radical resection has been performed. A modified fundoplication at the anastomosis seems to be the simplest technique and may be relatively effective in controlling symptoms. The impact of strategies to reduce reflux on quality of life and on pathological sequelae of reflux in the oesophageal remnant remains to be evaluated.
Laparoscopic reoperative antireflux surgery is feasible. Reoperation is likely to be more difficult following failure of an open procedure than a laparoscopic one.
The effects of posture on gastric emptying, intragastric distribution, and antropyloroduodenal motility after ingestion of a nonnutrient liquid have been evaluated. In seven healthy volunteers antropyloroduodenal pressures were measured for 30 min after ingestion of 150 ml of normal saline in two different positions: sitting and left lateral. Saline drinks were radiolabeled and ingested both before and after intravenous atropine (4 micrograms/kg). Rates of emptying from both the total (P < 0.05) and the proximal (P < 0.05) stomach were faster in the sitting position than in the left lateral position. There were more long (> 6 cm) antropyloric pressure waves (P < 0.05) and isolated pyloric pressure waves (P < 0.05) in the sitting position. Intravenous atropine slowed emptying in both positions (P < 0.05) and in the sitting position decreased (P < 0.05) the number of antropyloric pressure waves. After atropine, gastric emptying was also faster in the sitting compared with the decubitus position (P < 0.05), although there was no difference in antropyloric or isolated pyloric pressure waves between the two postures. We conclude that the effects of gravity on gastric emptying of nonnutrient liquids are likely to reflect changes in both antropyloric motility and intragastric distribution.
Carbon dioxide insufflation results in tumor dissemination during laparoscopy, leading to port site metastasis. Gasless laparoscopy may prevent this problem.
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