Acute pancreatitis as a first manifestation of primary hyperparathyroidism (PHPT) caused by parathyroid adenoma is exceptionally rare. A 24 year old female presented with pain in the left side of chest , upper abdomen and breathlessness. Laboratory studies showed elevated levels of calcium, amylase, lipase and parathormone. She was found to have associated gall stones, pancreatic and renal medullary calcifications and also left sided pleural effusion. Tc 99m scan showed increased activity of right inferior parathyroid gland. The patient underwent surgical resection of the functioning parathyroid adenoma. Although the actual causal relationship between hypercalcemia and pancreatitis has been a persistent topic of debate, detection of hypercalcemia may be a clue to diagnose PHPT due to parathyroid adenoma.
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