The influence of estradiolbenzoate, hydroprogesteroncapronate and pregnancy on the mechanical reaction of the directly and indirectly stimulated nerve-diaphragm preparation has been the subject of this investigation. Rats were ovario-ectomized and the hormone preparations were injected subcutaneously. After a lapse of 9 days the test preparation was made. 1. Estrogen and the estrogen-gestagen combination have a similar effect on the isometric contraction of the transversely striated muscle. The times of rising and relaxation were prolonged after indirect and direct stimulation. The contraction amplitude had not altered compared to the control group. 2. Gestagens and the hormone situation of pregnancy entail, independent of the kind of stimulation, a decrease of the tension progress and the speed of the tension increase. The gestagen-treated animals underwent a shortened contraction process. These findings enable us to comment on the different efficiencies of women during various cycle phases and during pregnancy.

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This study assessed the predictive value of acromial morphology in the treatment outcome of patients with impingement syndrome. Sixty-five patients with impingement syndrome were treated by a single orthopedic surgeon according to the same protocol and initially received the same conservative modalities. The incidence of acromial types in the nonoperative group was significantly different from those in the operative group (P=.008). A large proportion (88.9%) of the patients with type I acromions responded to conservative measures, while fewer (73.1%) patients with type II acromions responded to conservative measures. The majority (58.3%) of patients with type III acromions required surgical intervention. Acromial morphology appears to have a predictive value in determining the success of conservative measures and the need for surgery in patients with impingement syndrome.

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Im Unterschied zu dem in Abb. 1 gezeigten Verlauf bei floridem Ovarialkarzinom wird die HSRA bei erfolgreich behandelten Patientinnen im Normbereich gefunden. Die Reaktionen auf die Endoxankuren sind nicht annfihernd so ausgepr/igt wie in Abb. 1.Abbildung 2 zeigt den Spiegel der HSRA, bei 49 Patientinnen mit zytostatischer Therapie anhand der Mediane mit Konfidenzintervall wiedergegeben.Unsere Ergebnisse zeigen, dab die Bestimmung der Ribonukleaseaktivitfit im Serum ein aussagekraftiger Parameter in der Diagnostik und 121berwachung des Ovarialkarzinoms darstellt.