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By quenching polymerization with tritium-labelled methanol the total number of the metal-polymer bonds in the polymerization of ethylene and propylene by Ziegler-Natta catalysts was determined. Using the propagation rate constants determined by quenching polymerization with I4CO the rate constants of chain transfer with AIEt3 and Al(i-Bu)3 and the activation energy of chain transfer with AIEt3 were calculated.

The results of the associative study of predisposition to an elevated somatic mutagenesis in human lymphocytes determined by the test of TCR mutant cells (CD3-CD4+phenotype) for 251 females are presented. The presence of minor alleles of polymorphic sites of CYP1A1 gene, which increase the enzyme activity, correlated with the increasing spontaneous frequency of TCR mutant cells. The analysis of gaplotypes in CYP1A1 locus (3 sites) showed that a minor gaplotype of CG sites T3801C-T606G, which had a strong effect on the parameters of somatic mutation at the frequency of around 10%, has the maximum prognostic importance relative to the studied effects.

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