The distribution of the main frequencies of spontaneous rhythm of the small intestine in the 12.0-8.0 cycle/min range (by the aboral frequency gradient) was studied by the electrogastroenterographic method in healthy individuals and patients with stomach and colorectal cancer before and after gastrectomy and total removal of the large intestine. Organization of spontaneous rhythm of the small intestine on an empty stomach and after mixed food load in healthy individuals and changes in this organization in patients with stomach and colorectal cancer before and after total gastrectomy and complete removal of the large intestine were evaluated. The authors hypothesize that the stomach normally coordinates the small intestinal rhythm, while in stomach cancer this coordination is impaired. Changes in spontaneous rhythm of the small intestine (both in the proximal and distal portions) were detected in patients with colorectal cancer.

We studied the distribution of main frequencies of spontaneous activity (in the range of 2-4 cycles/min) of the stomach and large intestine in healthy individuals and patients with stomach and colon cancer before and after gastrectomy and resection or total colectomy. The rhythm was recorded noninvasively (from body surface) with Ag/AgCl electrodes connected to a 3-channel portable electrogastrograph. We determined general peculiarities of rhythm formation in the stomach and large intestine in healthy individuals on an empty stomach and after mixed feeding and evaluated changes in spontaneous activity in patients with stomach and colon cancer before and after gastrectomy, resection, or total colectomy. Rhythmic activity of the stomach was coordinated with that of the large intestine in healthy individuals, but not in patients with tumors before the start of specific therapy. Multichannel cutaneous electrogastroenterography and recording of spontaneous electrical activity in the epigastric and perianal regions reflect functional relationships between the stomach and large intestine.

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