Some aspects of magnet-driven liposome preparations used for the targeted delivery of drugs to organs, tissues, and guest microbe cells are considered. These liposome preparations contain encapsulated drug components and finely dispersed magnetic particles. A technology of the synthesis, purification, and stabilization of magnet-driven liposomes is proposed. Standardization of the liposomes with magnetite particles is based on the following characteristics: liposome size and structure, content of magnetite encapsulated in liposomes, and magnetic properties of the magnet-driven liposomes.

No abstract

No abstract

On the basis of silica - aluminosilicate, modified by carboxymethylated lignin and carbodiimide, obtained are the composite microgranulated magnetic immunoadsorbents (MIA) with high adsorption activity, which are characterized by the standardized structural characteristics and mechanical strength. Application of MIAs makes it possible, at the stage of tick samples preparation, to eliminate various admixtures via reiterative irrigations of the sorbent with the infectious agent fixed on it. Therefore negative influence of admixtures on the performed analysis is excluded, and the target agent is concentrated to the maximum limit. Thus the specificity and sensitivity of PCR-analysis enhances.