Dacarbazin (1) laBt sich polarographisch in Konzentrationen zwischen bis lo-' mol/l qualitativ und quantitativ bestimmen. Polarographisch aktiv ist die N=N-Gruppe, die unter Aufnahme van 4 Elektronen und 4 Protonen gespalten wird.
Polarolpephic and Colorimetric Determination of DacarbazineThe polarographic method is used for the identification and determination of Dacarbazine (1). The results indicate that 1 can be identified and determined as the pure compound or as a constituent of galenic preparations at concentrations between w 3 and mol/l. Polarographically active is the N=N-group, which is reduced by the addition of four electrons and four protons.Dacarbazin (1) ist ein neuartiges Krebschemotherapeutikum, das in den USA entwickelt worden i~t ' ,~,~) .
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