Abstract. A dog with a Iymphoproliferative disease resembling mycosis fungoides in ma n, the second reported canine case, had slowly progressive, multicentric cutaneous nodules and plaq ues. Ne arly half the body surface was involved. T he lesions consisted of multiple, flat, infiltrative, cutaneous tum ors composed of heterogeneou s, pleomorphic cells, some of which resembled histiocytes or ac tivated lymphocytes. Intracutaneous foci of tum or cells and numerou s tum or cells with bizarre con voluted nucle i were distinctive features that perm itted the lesion s to be distinguished from other non -epithelial cut ane ous neoplasms.
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