Various options in biotechnology have been exercised to produce industrially important metabolites from filamentous organisms. To select a suitable production strategy, the direct and indirect roles of morphological parameters in controlling bioprocess variables are observed. Some progress has been made in quantitation of morphology.Useful correlations have been reported in the literature in this avenue. Of course, some of the models, with proper modification, can be used to explain the morphological phenomena. This review is concerned with the application of morphological variables to correlate with bioprocess parameters for explaining optimal production strategy.