Objective: Appropriate regular physical activity is a major component in preventing the growing global burden of chronic disease and at least 60% of the global population fails to achieve the minimum recommendation of 30 minutes moderate intensity physical activity daily. This study was aimed at assessing the knowledge and practice of sedentary lifestyle among bankers in Bwari Area Council, FCT, Abuja in North-Central Nigeria.Methods: This was a descriptive cross sectional study using self administered questionnaire. Systematic sampling was used to recruit 257 bankers from the various banks within BAC. The data was analysed using EPI INFO computer software package (version 3.5.3). Results Conclusion:There was good knowledge of sedentary lifestyle among the respondents. More than half of the bankers were found to be sedentary and about a third were physically active. Programmes aimed at improving physical activity among employees of this occupation group are therefore advocated. Conclusion:Les répondants avaient une bonne connaissance du mode de vie sédentaire. Plus de la moitié des banquiers étaient sédentaires et environ un tiers étaient physiquement actifs. Des programmes visant à améliorer l'activité physique chez les employés de ce groupe professionnel sont donc préconisés. Mots-clés:Mode de vie sédentaire, Connaissance, Pratique, Abuja, Questionnaire global sur l'activité physique (GPAQ)