IntroductIon Biliary and pancreatic diseases, especially choledocholithiasis and neoplastic diseases, are commonly seen in elderly patients. Endoscopic retrograde cholangiopancreatography (ERCP) is a diagnostic and therapeutic procedure performed more and more frequently also in elderly patients. objEctIvEs The aim of this study was to evaluate the utility and safety of ERCP in patients >80 years of age. PAtIEnts And mEthods We retrospectively analyzed 821 ERCP performed in the Department of Gastrointestinal Diseases, Medical University of Łódź in the years 2005-2007. We compared age, sex, clinical symptoms, laboratory findings, ERCP efficacy and safety in patients >80 years of age versus younger subjects.