Abstract. Spontaneous infection withEncephalitozoonosis is caused by the obligate intracellular protozoan parasite Encephafitozoon cuniculi. The parasite and the associated lesions were recognized in rabbits in the early 1920s [9, 10, 291. Since then the disease has been described in many animals including mice [6, 151, rats [7], guinea pigs [13], nonhuman primates [1, 3, 211 and several species of carnivores [4,16,19,20,25, 261. Human infections also have been reported [12] but the causative organism in man is probably not identical to E. cuniculi [2, 11, 241.

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