tetramethoxyflavanone in addition to the known flavones chrysin, norwogonin, and wogonin were isolated from Scutellaria phyllostachya roots. The structures of the isolated compounds were established using IR, UV and PMR spectra.
In continuation of the study of flavonoids from plants of the genus Scutellaria L. (Lamiaceae) [1], we studied flavonoids from S. phyllostachya Juz. roots.Ground air-dried roots of S. phyllostachya that were collected in Namangan District of the Republic of Uzbekistan were extracted nine times at room temperature with ethanol (80%). The condensed alcoholic extract was diluted with water and worked up successively with CHCl 3 , EtOAc, and n-BuOH. The solvents were distilled off to afford CHCl 3 (20.0 g), EtOAc (15.0 g), and n-BuOH (23.0 g) extracts.The EtOAc extract (18.0 g) was chromatographed over a column of silica gel with gradient elution by CHCl 3 :i-PrOH (95:585:15). Elution of the column by CHCl 3 :i-PrOH (95:5) isolated chrysin-7-O-β-D-methylglucuronide (0.15 g) and apigenin-7-O-β-D-glucuronide (0.13 g). Elution of the column by CHCl 3 :i-PrOH (90:10) afforded baicalein-7-O-β-D-glucopyranoside (0.12 g). Finally, elution of the column by CHCl 3 :i-PrOH (85:15) isolated oroxyloside (0.18 g). The n-BuOH extract (23.0 g) was chromatographed over a column of silica gel with gradient elution by CHCl 3 :i-PrOH (95:585:15)
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