Introduction: Evidence-based intrapartum care uses the best available research on safety and effectiveness of specific practices to guide labor and delivery practice with the least harm intervention. Therefore this study was aimed to assess proportion of evidence-based intrapartum care and associated factors among obstetric care providers in Northwest Ethiopia, 2015.Methods: An institution based cross-sectional study was conducted. The data was collected using self-administered questionnaire from April to May 2015. The study sites were five referral hospitals in Northwest Ethiopia. All obstetric care providers registered in each referral hospitals were participated. Results:In adequate evidence is available towards intrapartum care, where the proportions of obstetric care providers practicing evidences during intrapartum phase were 38.3%. While using health information seldom for teaching (AOR=3.50, 95% CI=1.30, 9.40), providing in-service training for obstetric health care providers (AOR=4.52, 95% CI=1.61, 12.71), adequate knowledge (AOR=5.30, 95% CI=2.01, 13.90) and favorable attitude (AOR=3.34, 95% CI=1.30, 8.60). Conclusion:Obstetric care providers in Northwest Ethiopia were giving intrapartum care not guided by best evidence available. Further investigation is needed to stipulate on current Intrapartum care among obstetric care providers in northwest Ethiopia.