Structure lightweight has always been a hot topic in the field of engineering. Lattice structure has characteristics of light weight, high specific stiffness and high specific strength because of its high porosity and low relative density. It has been widely used in structural lightweight design. In addition, lattice structure has broad application prospects in advanced industrial equipment, due to the potential of anti-vibration, anti-impact, heat transfer and heat dissipation, zero/negative thermal expansion, electromagnetic wave absorption, sound absorption and noise reduction. In this paper, a design method of function-structure integrated lattice structure is proposed, topology optimization and variable density lattice filling technology are studied, the research methods of multi- functional characteristics of lattice structures are discussed, and the related simulation and experimental methods are introduced, which is of certain reference significance to the development of technology in this field.