No abstract

Heparin-induced thrombocytopenia Type II (HIT II) is based on a hypersensitivity to heparin and results in serious thromboembolic complications with a lethality of up to 23%. Due to its various manifestations -with or without thrombosis and/or a reduced number of thrombocytes -, a reliable diagnosis proves difficult and can only be made by a combination of clinical signs, thrombocytic behavior and antibody screening.

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A case is reported of Behçet's disease in a 41-year-old man, in the course of which colitis with perforation developed over two years, with fatal results. This is a rare complication of Behcet's disease and must be differentiated from ulcerative colitis and Crohn's disease. Blood transfusions have a limited therapeutic value in the terminal phase of the disease, which among others is characterized by a generalized depression of response of peripheral lymphocytes to stimulation.