The aims of this paper were to asses the quality of life with the use of the SF36 Questionnaire in patients with chronic heart failure and to establish the relationship between specific biochemical variables and the various aspects of the quality of life. The scores for various components of the quality of life were significantly affected by hemoglobin levels, creatinine clearance, fibrinogen levels and gamma-glutamyl-transferase levels, while lipid fractions and liver enzymes did not proove to have a significant impact on the quality of life.

Le rôle de l'élastographie par ondes de cisaillement dans le monitorage dynamique de la fibrose chez des patients présentant une hépatite C chronique avec réponse virologique soutenue suite à une thérapie antivirale directe Introduction. Au cours des dernières années, la pratique médicale actuelle a imposé des méthodes non invasives d'évaluation de la fibrose hépatique. L'objectif de l'étude était l'évaluation du rôle de l'élastographie 2D par ondes de cisaillement dans le suivi dynamique de la fibrose par rapport à une méthode validée-Fibromax. Matériaux et méthodes. 37 patients atteints d'hépatite C chronique et de fibrose avancée (F3 / F4) traités par Paritaprevir / Ritonavir + Ombitasvir + Dasabuvir ont été inclus à l'étude et l'évaluation a été réalisée au ABSTRACT Introduction. In the last years, the non-invasive methods of evaluating liver fibrosis were imposed in the current medical practice. The objective of the study was to evaluate the role of 2D Shear Wave elastography in the dynamic monitoring of liver fibrosis compared to a validated method-Fibromax. Materials and methods. 37 patients with chronic hepatitis C infection and advanced fibrosis (F3/F4) who received treatment with Paritaprevir/Ritonavir + Ombitasvir + Dasabuvir were included. The evaluation was done at baseline, 12 weeks after the end of treatment and 48 weeks after therapy. Results. There was a significant and positive correlation of high degree, according to the Spearman's rho correlation coefficient, between 2D Shear Wave elastography and Fibromax, showing very similar results both at the beginning of therapy (p<0.001, R=0.726)