The ectopic thyroid gland is a rare congenital disorder. It occurs in most cases at the level of the cervical midline and rarely in lateral submandibular topography. We present the case of a 44-year-old woman who consulted for a painful, progressively growing right submandibular tumor in which a diagnosis of ectopic multinodular goiter was made and surgical treatment by resection of the thyroid tissue was decided. She always presented normal thyroid function and the reason for surgery was the neck deformity that bothered the patient and the pain. In the postoperative period, she presented TSH of 40 and levothyroxine was started. We present this case because cases of submandibular ectopic multinodular goiter as the only functioning tissue are rare.

Esta obra está bajo una Licencia Creative CommonsAtribución 4.0 Internacional.

Background: pheochromocytoma is a catecholamine-secreting neuroendocrine tumor, with usual origin in the adrenal medulla. They are mostly diagnosed as adrenal incidentalomas in abdominal tomography (CT) or magnetic resonance imaging (MRI) or by related symptoms, as the classic triad including headaches, profuse sweating, and palpitations. Although it is a rare cause of secondary hypertension, this occurs in a great proportion of patients and it is usually sustained and paroxysmal. The biochemical diagnosis requires the dosage of plasmatic and/or urinary metanephrines and once confirmed, an imaging study such as CT or MRI must be requested to determine its location. Pheochromocytoma usually has low metastatic potential; treatment is adrenalectomy, conventional or laparoscopic, and resection can be curative. The reason for presenting these cases is to show two forms of presentation of a rare disease, with normal or hypertension, even in large tumors. Cases: We present four cases of Pheochromocytoma, two of which were diagnosed due to secondary hypertension and two as adrenal incidentalomas. In two of them the concomitant diagnosis of panic attacks and anxiety attacks was made, which sometimes shares clinical symptoms with the clinical picture of catecholamine’s excess. A 31-year-old man presents who presented with resistant hypertension and paroxysmal adrenergic crisis. A 46-year-old woman who presented with hypertension difficult to treat and adrenal incidentaloma. A 35-year-old woman who had big adrenal incidentaloma and normal blood pressure. A 34-year-old woman developed panic attacks and was found an adrenal incidentaloma on CT without hypertension. Conclusion: pheochromocytoma is a rare tumor that can have variable clinical presentations, with low malignant potential in the majority of the cases, and its accurate treatment relays on the clinical suspicion of this entity.

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