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ResumoObjetivo: Compreender a percepção dos profissionais de enfermagem frente à morte de recém-nascidos em UTIN. Metodologia: Trata-se de uma pesquisa exploratória, de campo, com metodologia qualitativa. Foram participantes da pesquisa 17 profissionais do quadro de enfermagem de uma UTI neonatal, sendo 05 enfermeiros e 12 técnicos de enfermagem. A coleta de dados foi realizada no mês de setembro de 2018 através de uma entrevista semi-estruturada contendo perguntas abertas e fechadas relacionadas ao tema, após parecer de aprovação n° 2.904.499, CAAE 91426218.1.0000.5290. Resultados: A partir da análise de dados pode-se perceber que os profissionais de enfermagem ao lidarem com o óbito neonatal desenvolvem sentimentos considerados negativos como, por exemplo, tristeza, decepção e frustração. Ao desenvolverem tais sentimentos métodos de enfrentamento são utilizados pelos profissionais para auxiliarem no momento de luto, como o uso da religiosidade, sendo considerada uma estratégia para amenizar o sofrimento do profissional. Conclusão: Conclui-se que é necessário manter um olhar diferenciado para os profissionais de enfermagem que atuam em UTIN, visto que o ambiente é considerado complexo e que desenvolve nos profissionais conflitos emocionais durante sua vivência, o que pode vir a trazer prejuízos para a sua saúde. Nursing professionals' experience of neonatal deathVivência dos profissionais de enfermagem perante a morte neonatal Recebido em: 24/11/18. Aceito em: 15/04/19. Como citar esse artigo. Lima, GR; Silva, JSLG. Vivência dos profissionais de enfermagem perante a morte neonatal. Revista Pró-UniverSUS. 2019 Jan./Jul.; 10 (1): 38-41. AbstractObjective: To understand the perception of nursing professionals regarding the death of newborns in NICUs. Methodology: This is an exploratory, field research, with a qualitative methodology. Nineteen professionals from the nursing staff of a neonatal intensive care unit participated in the study, of whom 05 were nurses and 12 were nursing technicians. Data collection was carried out in September 2018 through a semi-structured interview containing open and closed questions related to the topic, after approval no. 2,904,499, CAAE 91426218.1.0000.5290. Results: Based on data analysis, it can be seen that nursing professionals in dealing with neonatal death develop negative feelings, such as sadness, disappointment and frustration. In developing such feelings methods of coping are used by professionals to assist in the moment of mourning, such as the use of religiosity, being considered a strategy to soften the suffering of the professional. Conclusion: It is concluded that it is necessary to maintain a different perspective for the nursing professionals who work in NICU, since the environment is considered complex and that develops in the professionals emotional conflicts during their experience, which can bring damages to their health.

In mussels, stress signals such as heat, osmotic shock and hypoxia lead to the activation of the phosphorylated p38 mitogen activated protein kinase (pp38-MAPK). This stress activated protein has been efficiently used as a biomarker to several natural and anthropogenic stresses. However, what has not been tested is whether differences in gender or size can affect the response of this biomarker. The present study tested whether there was variation in the expression of pp38-MAPK in mussels Perna perna of different gender and size classes when exposed to natural stress conditions, such as air exposure. The results show that gender does not affect the expression of pp38-MAPK. However, size does have an effect, where mussels smaller than 6.5 cm displayed significantly (p<0.05) lower levels of pp38-MAPK when compared to those larger than 7 cm. Mussels are one of the most used bioindicator species and the use of biomarkers to determine the health status of an ecosystem has been greatly increasing over the years. The present study highlights the importance of using mussels of similar size classes when performing experiments using stress-related biomarkers.

Visceral adipose tissue (VAT) is associated with various metabolic disorders, and adipokines, secreted by adipose tissue, are involved in their pathogenesis. This study investigated associations between VAT/subcutaneous adipose tissue (SAT) ratio, inflammatory markers, and cardiovascular (CV) risk-score in adults. Plasma levels of adipokines, plasma lipid profile, blood pressure, and body composition (using dual-emission x-ray absorptiometry) were determined. CV risk-score based on the American College of Cardiology and the American Heart Association (ACC/AHA) score was calculated in a sample of 309 Brazilian civil servants aged o60 years. Participants' VAT/SAT ratio were categorized into quartiles. Among males, plasma leptin (2.8 ng/mL) and C reactive protein (CRP) (0.2 mg/dL) (Po0.05) levels were higher at P75 and P50 than P5, and the highest calculated CV risk-score was observed at P75 (7.1%). Among females, higher plasma adiponectin levels were observed at P25 (54.3 ng/mL) compared with P75 (36 ng/mL) (Po0.05). Higher plasma CRP levels were observed at P75 (0.4 mg/dL) compared with P5 (0.1 mg/dL) (Po0.05). Higher CV risk-score was observed at P75 (2.0%) compared with P5 (0.7%). In both sexes, VAT and VAT/SAT ratio were directly associated with plasma leptin, CRP, and CV risk-score, and inversely associated with adiponectin; SAT was directly associated with plasma leptin and CRP (Po0.01); interleukin (IL)-10 and CRP were directly associated with adiponectin and leptin, respectively (Po0.05). Among men only, IL-10 (inversely) and CRP (directly) were associated with CV risk-score (P=0.02). Our results strengthened the relevance of the VAT/SAT ratio in cardiovascular risk.

Obesity in adolescents has reached epidemic proportions and is associated with the inflammatory response and viral infections. The aim of this study was to understand the profile of inflammatory cytokines and chemokines associated with the inflammatory response and metabolic syndrome (MetS) in obese adolescents with positive serology for adenovirus 36 (ADV36). Thirty-six overweight, 36 obese, and 25 severe obesity adolescents aged 10 to 16 years were included in the study. The following variables were analyzed: sex, age, body mass index (BMI), blood pressure, total cholesterol and fractions, triglycerides, glucose, serum cytokine concentrations, and ADV36 antibodies. Cytokines and chemokines were quantified by cytometry and ADV36 serology was determined by enzyme-linked immunosorbent assay (ELISA). The results showed higher levels of the cytokines interleukin-1beta (IL-1β), IL-6, IL-10 and of the chemokine interferon-gamma-inducible protein 10 (IP-10) in severe obesity adolescents compared to the obese and overweight groups, as well as in the group with MetS compared to the group without this syndrome. The frequency of ADV36-positive individuals did not differ between groups. The findings revealed differences in BMI between the obese and severe obesity groups versus the overweight group in the presence of positivity for ADV36, suggesting an association with weight gain and possibly MetS installation.