The Chronic Granulomatous Disease is a rare primary immunodeficiency disease, principally attacking white blood cells, characterized by an increased susceptibility to the recurrent bacterial and fungal infections along with the genesis of granulomas in tissue. Staphylococcus and aspergillosis are the main pathogens responsible for majority of infections in CGD. Here we report a case of 5yrs old boy who came with the complaints of fever, cough, and multiple abscess over the right leg, right ankle and left hand with puss discharge. DHR test was performed and have shown the positive results for chronic granulomatous disease.

The design of the work is to describe brain tuberculoma in an adolescent. Tuberculoma is defined as the unfamiliar incidence of tuberculosis in divergent parts of the body Fifty years of Tuberculosis Control projects have been abortive in declining the prevalence of the infection in major parts of the world even after using potentially potent drugs however TB persists to kill all age groups. We report the case of a 14 years old boy presented with history of seizures associated with altered consciousness, unrolling of eyes, frothing from angle of mouth, tongue bite, vomiting and post ictal confusion, weakness and blurred vision of left eye. He had three indistinguishable incidents of seizures. The presented case has been recovering by using anti-tubercular treatment. Early diagnosis will make the disease worsen less and it makes patient to respond well to treatment provided.

Allergic rhinitis is an IgE antibody mediated, inflammatory disease.The most commonly encountered risk factors for allergic rhinitis are presence of atopy, asthma, eczema, and other allergic illnesses. Identification of aeroallergens helps in patient counseling to modify life style and prevent exposure to triggering factors.To determine the prevalence of aeroallergens in allergic rhinitis. This was a prospective study done in cases of allergic rhinitis over a duration of one year from January 2019 to December 2019. Complete history taking was followed by ENT examination including Rhinoscopy and endoscopy, peripheral smear examination for eosinophils, absolute eosinophil count testing and Skin prick testing with known allergens and serum IgE level testing. A total of 145 cases of allergic rhinitis were studied. The patient age ranged from 11 years to 50 years. The male to female ratio was 0.5:1. Most common allergen causing allergic rhinitis was dust mite which constituted about 44.1% cases. The next common allergen was Mold which accounted for 20.6% cases. We conclude that there are numerous aeroallergens that can cause allergic rhinitis and the most common ones are dust mites, molds, house dust, animal dander, pollen and others. Correct identification of the aeroallergen helps in the proper counseling of the patients so as to prevent exposure to those aeroallergens thereby reducing the episodes and severity of allergic rhinitis.