The purpose of this article is to present the results of the ongoing study of the University digital transformation on the basis of a comprehensive theoretical model. The article describes a conceptual model of the University digital transformation formed based on the comprehensive quantitative and qualitative analysis of potential ecosystem participants in line with the requirements of changing external conditions. The authors list the current results of the transformation and strategic plans considering any achievements adjustment. The National University of Science and Technology “MISiS” (NUST MISiS) has been used as an experimental basis for the research. The key achievement of NUST MISiS such as a digital ecosystem is described in this article. The digital environment of NUST MISiS considers the needs of the University staff and students and contributes to achieving the strategic goals.