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Differing with the type of cancer cells, thymoquinone posseses a strong contentration and time dependent survival reducing effect on cancer cells via apoptosis (Fig. 6, Ref. 22). Text in PDF www.elis.sk.

<p class="Abstract">The aim of this study was to reveal the phytochemical constituents, antioxidant and antimicrobial activity of <em>Ajuga orientalis</em>. According to the antimicrobial results, the methanol extract of<em> A. orientalis</em> showed a MIC value of 312.5 µg/mL against the tested pathogenic bacterial strains. Anticandidal activity of extract was found as 156.3 µg/mL both against <em>Candida albicans</em> and <em>C. parapsilosis</em> strains. Whereas the extract was more effective against <em>C. tropicalis</em> with the MIC value of 78.1 µg/mL. The<em> in vitro</em> DPPH radical scavenging activity of the extract was determined as IC₅₀=0.4 ± 0.02 mg/mL whereas the standard BHT IC₅₀ was 0.01 ± 0.00 mg/mL. Trolox Equivalent Antioxidant Capacity (TEAC) of extract was determined 1.3 mM TEAC, while BHT, 1.9 mM TEAC.</p><p> </p>