Summary. Aldehyde dehydrogenase (ALDH) activity is demonstrated in four strains of D. melanogaster lacking active alcohol dehydrogenase (ADH-nuU mutants). In the four strains, ALDH activities are similar to those found in a wild strain. It is concluded that ADH-null flies are able to detoxify acetaldehyde. This finding is discussed in relation with the dual function of ADH proposed recently.
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