Sprain are acute injuries that occur to the ligaments. Therefore, there is a requirement for health education by performing appropriate first aid using the audiovisual method. An educational media uses the senses of hearing and sight to facilitate the delivery of exciting material. This study adopted a quasi-experiment with one group pre-test and post-test without control design. The sampling technique was non-probability sampling with the total sampling technique of 20 futsal players. Respondents' knowledge of Sprain first aid in the pre-intervention was in the poor category with 11 respondents (55%). In the post-intervention, 17 respondents (85%) had good knowledge of Sprain first aid. The Wilcoxon test results presented the knowledge level of Sprain first aid in futsal players with p-value = 0.000 (p-value <0.05). Therefore, there was an effect of health education about Sprain first aid with audiovisual media on the knowledge level of futsal players in Surakarta. .

Earthquakes in Indonesia cause physical damage as well as fatalities, high mortality rates and disability when an earthquake occurs, it is necessary to reduce or prevent it by increasing people's knowledge and skills about how to evacuate during an earthquake. Earthquakes that are not resolved with resilience and lack of human resources that can handle earthquakes from pre-disaster, during disaster and post-disaster. Earthquakes are caused by the movement of the Earth's crust (Earth's plates). The frequency of a region, refers to the type and size of earthquakes experienced over a period of time. Earthquakes are measured using a seismometer. Moment magnitude is the most common scale where earthquakes occur throughout the world so that the community is demanded to be prepared, one of which is evacuation during a disaster which is held by evacuation counseling in Wonorejo Village, Karanganyar. earthquake with pre-test data 75% of the residents did not know and after counseling and post-testing it was found that 90% of the residents understood the skills and knowledge of evacuation during an earthquake. with the lack of knowledge and skills of residents regarding evacuation during an earthquake, it is very appropriate for residents to understand when an earthquake occurs

ABSTRAK Neurotensin merupakan protein yang memiliki fungsi ganda dan bekerja di otak dan usus sehingga sering disebut sebagai neuropeptida yang berperan sebagai neurtrasmitter saat di otak di otak dan disebut hormon saat berada di gastrointestinal dan bertujuan mengatur gerakan lambung,duodenum dan usus, serta sekresi asam lambung, penyerapan klorida dan air di usus besar, keberadaan neurotensin paling banyak terdapat di jejunoileum yaitu 85% dan neurotensin reseptor-1(NTSR-1) adalah reseptor terbanyak di jejunoileum. Makanan rendah lemak adalah makanan yang memiliki kadar lemak di bawah 25% dan memiliki pengaruh terhadap motilitas usus dan juga otak. Tujuan penelitian untuk mengetahui pengaruh pemberian makanan rendah lemak terhadap morfologi sel dan ekspresi reseptor-1 neurotensin (NTSR-1) di mukosa usus. Tikus wistar jantan berusia 3 bulan berjumlah 20 ekor di bagi kedalam 2 kelompok, Kelompok 1 diberikan makanan rendah lemak AIN 93 M kelompok 2 diberikan pakan tinggi lemak AIN-93G, perlakuan dilakukan selama 30 hari, kemudian dilakukan pemeriksaan Imunnohistokimia (IHC) dan pembacaannya menggunakan software IHC reader yang menghitung berdasarkan penyerapan warna pada slide,dan dilakukan pemeriksaan Hemotoxilin Eosin untuk mengetahui morfologi sel di usus Penelitian ini menunjukkan hasil rerata yaitu: kelompok 1 dengan pakan standar yaitu AIN 93M menunjukkan hasil rerata 51,08± 18,13 dengan rentang nilai 6,03-96,14. kelompok 2 dengan pakan AIN 93G didapatkan hasil 107,74± 18,67 dengan rentang nilai 61,34-154,13. Hasil pengamatan IHC pada pewarnaan HE menunjukkan tidak ada perubahan morfologi pada sel usus. Hasil penelitian menunjukkan bahwa dengan pemberian makanan tinggi lemak (AIN 93 G) dapat memicu sekresi neurotensin lebih tinggi. Makanan rendah lemak (AIN 93 M) tidak memicu sekresi neurotensin dan tidak merubah morfologi sel usus.   Kata kunci: neurotensin, , jejunoileum, imunohistokimia     .ABSTRACT Neurotensin is a protein that has a dual function and work in the brain and the gut so often referred to as neuropeptides that act as neurtrasmitter current in the brain in the brain and is called hormone while in the gastrointestinal and respiratory stomach, duodenum and colon, as well as acid secretion Stomach, chloride and air absorption in the colon, found most neurotensin in jejunoileum ie 85% and neurotensin receptor-1 (NTSR-1) receptors in jejunoileum. Low-fat foods are foods that have a fat content below 25% and have an effect on the motility of the intestine and also the brain.This study aimed to determine the effect of food on the fat and cell morphology and expression of neurotensin receptor-1 (NTSR-1) in the intestinal mucosa. Rats Wistar male aged 3 months to 20 fish inside into two groups, Group 1 was given a low fat diet AIN 93 M group 2 is given high feed fat AIN-93g, this treatment is carried out for 30 days, then examined Imunnohistokimia (IHC) and the reading using IHC reader software that calculates based on the color absorption on the slide, and Hemotoxilin Eosin examination to determine the morphology of cells in the intestin. This study showed that the average results: group 1 with a standard feed that is AIN 93m shows the results mean 51.08 ± 18.13 with a range of values from 6.03 to 96.14. Group 2 with AIN 93G feed result of 107,74 ± 18,67 with value range 61,34-154,13. And the result of IHC observation on HE staining shows no morphological changes in intestinal cells. The results of this study showed that using a high-fat diet (AIN 93 G) could pass the secretion of higher neurotensin. Low-fat foods (AIN 93 M) do not escape neurotensin secretion and can not alter the morphology of intestinal cells.   Keywords: neurotensin ,, jejunoileum, immunohistochemistry

Background: The main problem in taekwondo athletes is the lack of knowledge and skills in handling sprain injuries using the PRICE technique. Protection, Rest, Ice, Compression and Elevation is a non-pharmacological therapy for the treatment of sprains. Sprain injury handling skills with PRICE can be taught to anyone, especially taekwondo athletes through Instagram media and training on simulation methods so that they have good skills in handling sprain injuries. This study aims to determine the effect of education through Instagram media and simulations on the skills of handling sprain injuries in taekwondo athletes. Methods: The research used quasi-experimental design which involve pre-posttest with control group. The population was Taekwondo athlete community in Central Java. Samples were selected with total sampling technique. Subjects were 68 respondents consisting of 34 in each group obtained by simple random sampling technique. Education using video, leaflet and simulation provided to the control group, while the treatment group obtained material via instagram story, reels, videos, captions on Instagram and simulation. The measurement of Sprain injury management skills was using observation sheet. Mann whiney test performed the analysis. Results: The results showed that sprain injury management skills score increases significantly in those two groups (p-value:0.000; α;0.05). The treatment group showed a higher increases of that sprain injury management skills than control group. Conclusion: The finding highlights education using instagram and simulation is effective to increasing sprain injury management skills of Taekwondo athlete. It is recommended to apply instagram and simulation in order to upgrading the skills.

Kemoterapi merupakan salah satu penatalaksanaan pasien kanker. Namun, obat kemoterapi dapat merusak sel mukosa normal, menyebabkan inflamasi, pembentukan lesi dan ulserasi sehingga mencetuskan cedera sel mukosa (mukositis). Reaktivitas radikal bebas akibat kemoterapi dapat dihambat oleh sistem antioksidan yang terdapat pada sayuran dan buah-buahan.Berkumur air kelapa muda direkomen-dasikan dalam tindakan oral care. Penelitian ini bertujuan untuk mengetahui pengaruh berkumur air kelapa muda terhadap mukositis akibat kemoterapi pada pasien anak. Penelitian kuantitatif pre test post test control group design dengan instrumen Oral Assasment Guide pada 15 responden kelompok intervensi dan 15 responden kelompok kontrol dengan teknik simple random sampling. Hasil uji statistik paired t-test menunjukkan terdapat penurunan yang signifikan pada rerata skor mukositis setelah intervensi pada kelompok intervensi (p=0.000). Peneliti menyim-pulkan berkumur air kelapa muda dalam tindakan oral care dapat menurunkan mukositis akibat kemoterapi, sehingga diharapkan hasil penelitian ini dapat diaplikasikan dalam protokol oral care pada anak yang menjalani kemoterapi sebagai bagian dari penerapan ilmu komplementer.