COVID-19 is a disease caused by coronavirus; it is also called a SARS-COV-2 virus. Over the last six months, it has spread rapidly worldwide and made it a pandemic. The pandemic has forced people to stay indoors and work, which may increase chronic diseases among them. Immunomodulators are the substances which influence the immune system. It includes some medications as well as some activities like exercise, Yoga, meditation etc. Elderly citizens who used to walk generally before lockdown may suffer from pedestrian problems including hyperthyroidism, sugar problems blood. When the media used to do the work regularly, we had one kind of stress to do all the desired or targeted work on time. But now the person became very lazy due to self-reliant schedule that may lead to many diseases. So physical exercise is essential in this pandemic situation. Physical activity results in better immune response, which may result in many health benefits. An individual who regularly does physical exercises is healthy and fit in every aspect that can beat any of the diseases. It can also refine cardiovascular risk factor. In addition to this, it also enhances - pro thrombogenesis, improves endothelial functions, increases inculcation, depletes sympathetic tone and some other undefined factors. But all these have been put at bay due to Covid-19 pandemic. It is challenging to keep up an exercise routine due to daily restricted movements. Physical exercise helps in boosting the immune system of our body which reduces stress, anxiety. Brain gets the supplement of endorphins, chemicals that revitalise one's mind and body enriching the mental and spiritual faculty of an individual.