Paraganglioma-like dermal melanocytic tumor (PDMT) is a rare subtype of benign dermal melanocytic tumor, first described in 2004. Its histopathologic features resemble those of paraganglioma, showing presence of a distinctive partitioning of the tumor into small and large packets, nests, or short cords by delicate fibrous septa (zellballen pattern). But the immunostaining characteristics are those of melanocytic lesions, as PDMT express S-100, melan A, HMB 45 and lack pancytokeratin markers. It has a benign course, although a lesion of low malignant potential cannot be excluded. We describe a case of 60-year-old female who presented with three PDMT lesions on her right leg. To the best of our knowledge this is the first case reported from India.
Background: Cystic lesions of pancreas though uncommon are being increasingly identified as a result of developments in imaging techniques. Rapid advances in pancreatic surgeries associated with better patient outcome have led to a variety of pancreatic lesions being increasingly resected and pathologically diagnosed. Newer entities and classification systems have emerged.Methods: This was a hospital based study conducted in the Department of Pathology, Academy of Medical sciences, Pariyaram. In the 91pancreatic resections done over a period of 3 years from 2013-2016 ,there were 15 cases of cystic pancreatic lesions which formed the subject of the present study.Result: Cystic pancreatic lesions constituted 16.5% of cases (15 cases) of the 91 pancreatic resections done for various reasons. Of the 15 cases there were 4 non-neoplastic cysts all of which were pancreatic pseudocysts with a M:F ratio of 3:1. There were 11 neoplastic cystic lesions with 4 serous cystadenomas, 3 solid papillary pseudotumors , 2 mucinous cystadenomas and 1 case each of invasive adenocarcinoma in Intraductal Papillary Mucinous Neoplasm (IPMN) and IPMN with low grade dysplasia Except for the one patient with invasive adenocarcinoma in IPMN all others with neoplastic lesions were females. Age of the patients ranged from 14-67 yrs. Conclusion:Cystic tumors of the pancreas are more common in females with the majority of the tumors being benign when compared to ductal adenocarcinomas which are aggressive tumors with higher incidence in males. The possibility of Solid papillary pseudotumor should always be considered in young females presenting with an encapsulated pancreatic mass especially in the tail of pancreas.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.