An innovative approach of combining membrane and zero brine technologies for a joint treatment of industrial liquid waste is investigated regarding its environmental impacts compared to the existing liquid waste treatment. The object of investigation is the generation of waste acid solution by a hot dip galvanizing plant in Sicily, Italy. The waste acid solution contains hydrochloric acid, iron and zinc, which makes it a hazardous waste according to EU classifications. Environmental impacts are studied for two scenarios in the Tecnozinco hot-dip galvanizing plant in Sicily, Italy: (i) the current process of pickling with linear disposal of waste acid and (ii) the pickling combined with in-situ treatment of the waste acid using a combination of diffusion dialysis (DD), membrane distillation (MD) and a precipitation reactor. Results are obtained via an attributional life cycle assessment (LCA) approach focusing on the water footprint profile of the process. The linear disposal path creates significant costs, environmental burdens and risks during the 1500 km transport of hazardous liquid waste. The combination of DD and MD, complemented with a zero-brine precipitation reactor, closes internal material loops, could save local water resources and reduces costs as well as environmental impacts. Reduction potentials of 70–80% regarding most LCA impact categories can be expected for the application of the novel technology combination supporting the galvanizing pre-treatment process under study. Therefore, the application of such technology on the way forward to a more circular economy is recommended from an environmental viewpoint, especially in process plants similar to the investigated one. Graphical Abstract