A cluster of nine severe local reactions occurred in a Pennsylvania school district following a mass measles immunization program in February 1981. A case-control study showed that the nine cases had a statistically significant increased history of having received killed measles vaccine previously (p < .001, Fisher's exact test) and a statistically significant higher geometric mean measles antibody titer (p < .01, Student's t test) than controls, suggesting that previous receipt of killed measles vaccine was the underlying cause of these reactions. (Am J Public Health 1983; 73:899-900.)
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