Signal intensity changes on 1.5-T FLAIR MR images can be used as a surrogate marker of stroke age, either qualitatively or quantitatively. This suggests that MR imaging might be used as a "clock" for determining stroke age in patients with an unknown onset time, potentially increasing the number of patients who are eligible for thrombolysis.
It is shown that by aggregating simple random parameters, processes such as autoregressive micro-relationships or Ornstein-Uhlenbeck processes, one can obtain various seasonal long memory Gaussian models. The investigation concerns the discrete as well as the continuous time setting. In both situations the precise asymptotic behaviour of the covariance is studied. The regularity of sample paths is evaluated when possible.
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