Introduction: Natural heritage is becoming an increasingly important focus in international and national policies. Bulgaria has a large diversity of natural resources with protected areas. Natural resources are the main product in wellness tourism, which will grow in 2022 with an impressive 7.5% growth per year. According to the Global Wellness Institute Report, this is a higher percentage than the total revenue of the whole world tourism (6.4%). Methods: We systematically develop and analyze innovative wellness programs for people of all ages. We are making the first attempt to create some simulated products (in blocking mode) with augmented virtual reality. Results: Immune system health will remain an important social issue in 2022. The focus will stay on the individual consumer and the new health strategies. Scientific evidence is accumulating about holistic approaches, health from contact with nature, a balanced diet, and microbiome, which are key to achieving a wellness lifestyle. Programs to strengthen the immune and metabolic health and individual psycho-relaxation practices in and from the natural heritage will be increasingly important. Discussion: Effective wellness practices in forests and sea are slow modeling strategies that prove their effectiveness and positive influences but require regular practice. Conclusion: The Wellness lifestyle requires communicating regularly with nature. It is globally important to preserve natural heritage, eat a balanced diet, and invest in personal health to achieve a Well-being.