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An attempt is made to estimate the seasonal source function, Q, of CO, on the basis of data for the biosphere, provided by Lieth, and for other sources. The variation of soil respiration appears to be the most uncertain factor. The resulting CO, variations in the atmosphere are calculated for horizontal exchange coefficients, K, which vary with latitude. Comparison with observations given by Bolin & Keeling shows that the results are not very sensitive with respect to the assumed variations of Q and of K with latitude. Previous results on the 0, budget are used to calculate seasonal variations of tropospheric 0, for stratospheric injection rates, and K values which vary with latitude. It is concluded that tropospheric 0, may be a useful tracer for the study of the global exchange mechanisms between stratosphere and troposphere, and of related problems.