AbstrakHerpes Simpleks Keratitis (HSK) merupakan salah satu penyebab kerusakan kornea. HSK terjadi akibat infeksi Herpes Simplex Virus tipe 1 (HSV-1). HSK memiliki manifestasi klinik dari epitel sampai endotel. Diagnosis didukung dengan penurunan sensibilitas kornea, pemeriksaan Giemsa dan Papaniculou. Terapi tergantung pada temuan klinis, yang bisa merupakan kontraindikasi untuk manifestasi yang berbeda. Tujuan penelitian ini adalah untuk menggambarkan variasi kasus HSK, manifestasi klinis dan managemen. Metode: Studi retrospektif dari data rekam medik bulan Januari 2012-Desember 2013, Bagian Mata, RS.M.Djamil. Pasien HSK sebanyak 52 orang, bilateral 6 orang (58 mata), wanita 50%, pria 50%. Pasien terbanyak pada kelompok usia 31-40 th (26,9%). Tipe keratitis terdiri atas Epitelial 18 mata, Stromal 22 mata, gabungan 12 mata, Keratouveitis 4 mata dan Neurotropik Keratopati 2 mata. Pemeriksaan penunjang dengan tes sensibilitas kornea, Giemsa dan Papanicolou. Terapi yang diberikan antara lain Acyclovir salep mata, Acyclovir oral, Kortikosteroid tetes mata. Perbaikan visus paling banyak pada tipe keratitis stromal, 9 mata(40,9%) dan kombinasi, 9 mata(75%). Loss Case banyak pada keratitis epitelial, 11 mata(61,1%) karena pasien tidak kontrol kembali. Pemeriksaan Giemsa ditemukan Mononuclear Cell 21, Giant cell positif 12, Papanicolou positif 6. Semua kasus didapatkan penurunan sensibilitas kornea.Terapi yang diberikan Acyclovir salep mata, Acyclovir oral, Kortikosteroid tetes. Amnion Graft Transplantation dilakukan pada 2 kasus. Kasus terbanyak ditemukan tipe stromal 22 (37,9%) dengan bilateral 6 (10,3%) dan perbaikan visus (39,6%). Abstract Herpes simples keratitis (HSK) is a leading cause of corneal blindness worldwide. HSK result from an infection withHerpes Simplex Virus type 1 (HSV-1). Herpes Simplex Keratitis (HSK) appears with much clinical manifestation, from epithel to endohel. Diagnose supported by decrease of corneal sensibility, Giemsa staining, Papanicolou test. The treatments depend on the clinical finding, and will be contra indicated for other manifestation. The objective of this study was to describe HSK cases, Clinical Manifestation and Management. Retrospective study was obtained medical record from January 2012 to 2013 at Department of Ophthalmology, M. Djamil Hospital. Patients HSK were 52 persons, bilateral 6 (58 eyes), females 50%, male 50%. Patient mainly in the age group 31-40 (26,9%). Type of keratitis consist of Epithelial 18 eyes, Stromal 22 eyes, combines forms 12 eyes, Keratouvetis 4 eyes, and Neurotropic Keratopathy 2 eyes. Ancillary test with corneal sensibility, Giemsa staining, Papanicolou. The treatment was Acyclovir ointment, Acyclovir oral, Corticosteroid eye drop.The most improvement visual acuity was stromal keratitis 9(40,9%) and combines forms 9 (75%). Loss case in epithelial keratitis 11 (61,1%) cause patient didn't comeback. Giemsa staining dominant found Mononuclear Cell 21, Giant cell positive 12, Papanicolou positive 6. The all cases, decrease of corneal sensibility, Treat...
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