With the development of digital technology, Vietnam's education has been undergoing significant changes. This is considered one of the eight important fields of the National Digital Transformation, so it needs to take advantage of opportunities to be able to train high-quality human resources according to international standards. Beside, the Covid-19 pandemic has quickly put pressure on the previously predicted trends in education such as the “Future University”. This paper shows the data of an investigation on the factors affecting the readiness of Vietnamese students for digital transformation in the above context. The data is built based on the TAM model and sociological investigation method to collect multidimensional information from many perspectives of different individuals to have a basis for assessing the level of influence. The survey includes the main questions corresponding to the independent variables in the model: Self-study ability, Attitude, Perceived Usefulness, Perceived Ease of Use, and Covid-19. The authors distributed the questionnaire online and collected 913 valid responses.