Dysprosium recovery is essential for the sustainable development of clean energies. The present paper investigates the continuous adsorption and recovery of Dy from aqueous solutions using a fixed bed of expanded vermiculite. The study was divided into operational conditions optimizing, modeling, regeneration and reuse cycles, characterization of the regenerated adsorbent, and column selectivity analysis. Under the best conditions, high breakthrough (q b ) and equilibrium (q e ) capacities of 0.31 and 0.42 mmol/g were achieved. The Yan and DualSD models adjusted the data well and can be applied for future scale-up simulations. The fixed bed could operate efficiently, maintaining an average q b of 0.31 mmol/g and q e of 0.45 mmol/g over the five cycles. The spent adsorbent presented textural properties different from the original, indicating that the desorption steps did not completely regenerate the material. The selectivity toward dysprosium was confirmed since the removal of Dy (82%) was at least twice the adsorption efficiency of Pb (41.1%), Ni (35.7%), Cd, and Cu (∼16.5%). Thus, the recovery of dysprosium using a fixed bed of expanded vermiculite is reproductive along with several uses. Also, the material has a natural selectivity with potential for further advancement of engineered adsorbents based on vermiculite.