No abstract

As in a cops and robbers play we discover new mycotoxins and metabolites everyday and we are forced to develop new molecules quickly as chemo-or biosensors or to modify existing molecules able to recognize these new hazardous compounds. This will result in an enormous cost saving to agro-food industry through the prevention and reduction of product recalls and reduced treatment costs. Here we present a brief review of the rapid methods used to detect mycotoxins, considering usefulness and limits. Then we propose a new fast, efficient and cheap methodology, based on a combination of computer chemistry aided design and fluorescence, that can help to drive synthesis in a more efficient way.

No abstract

No abstract

enhance tile Lewis basicity of tile adjacent nitrogen atom(:-~L It has further been shown that a band m the 2820-2700 cm region, presumably due to C-H stretching, should disappear upon coordination of this nitrogen to the metal ion<-+3L The absence of a band in this region in the 3,3-Me2Cz complex indicates coordination of the nitrogen atom attached to the methyl groups in this complex. Tile presence of an N(31 methyl group in 2,3-MeeCz would enhance the Lewis basicitv of this nitrogen. It is therefore assumed that this nitrogen is involved in coordination in its complex. Tile similar ligand [MeNHNMeCS2]-is coordinated 1241 through this nitrogen to nickel N(3) coordination is possible because the inductive effect of the methvl group may balance the lowering of electron density on this nitrogen atonl due to the phenyl group.The N-N stretching vibration has been assigned on the basis of earlier work (el and occurs at ca. Ill(Ill cm I ill Cz, vehcther the resulting group is chelated or not. Tile distiction between chelated and nonchelated carbazic acid has been made ~=~ only because this band broadens in the chelates. Tile presence of a slightly broad band m tile 1030-950 cm -J region in tile copper(ll ) complexes of N-substituted carbazic acids may taken its evidence for the nitrogen involvement in bond formation. AcknowledgementsThe author thanks the Director, Laboratorio di Tem-ia e Stuttura Electronica dei Composti Coordinazioni del CNR, Rome, italy, where part of the present work was cltrried ot, t. The CSIR and UGC. New Delhi are also thanked for financivl support.References ~ G. Base, R. L. Belford and R. E. Dickensen, bung. Chem., l, 438 (1962). -~1+, A. Chakravorty and S. Basu, J. lnoJ N. Nm'l. ('hem.. 17. 55 (IUhl). -iivj A. B. P. Lever, J. Lewis and R. S. Nyholm, J. ('hem. Sot,, 5262 (1962). - has been measured at liquid heliunl tetnperature using single crystals of Ke('rO4 doped with the ferrate(Vl) ion and a new band has been observed at 9112 cm -I . An interpretation of the spectrum in the 9(11111-22(11)11 cnl i range is given by consMering tile possible ligand field transition under tile cr...