Anorexia, as a symptom, is part of the complex picture of a large pediatric pathology. Through attentive observation, anorexia as a single sign, may announce the onset of serious and particular affections. In all 4 cases, anorexia was a singular sign for a period of time before the complete illness was established. Whether adenoid cyst, cerebral abscess, pontocerebellar atrophy, Wilms tumor, neuroendocrine system of hunger regulation, satiety, complex control achieved through interactions of the limbic-hypothalamus-cortex system, come into operation with the occurrence of organic anorexia, different of the psychogenic anorexia (usually common in adolescents). The study is an alarm signal on the importance of a symptom in early diagnosis, and the rapid establishment of therapy in severe life threatening conditions.

Aim: The authors have proposed to assess peripheral adenopathies in a series of hospitalized children in order to identify and define clinical and morphological profiles of different types of lymph node (LN) diseases. Materials and Methods: The studied group consisted of 58 patients less than 18 years of age. The investigation algorithm included: gender, age, site, involvement, side, extension and histopathological (HP) type of LN lesions. Tissue fragments were processed using classical histological techniques (formalin fixation and paraffin embedment) and stained with Hematoxylin-Eosin (HE). In some cases (tuberculous lesions and lymphomas), special stainings (Ziehl-Neelsen) and immunohistochemistry were used. Stratification scales of cases were defined according to each parameter in order to compare the data. All obtained data were assessed individually, compared to each other and with similar data from the literature with the help of a statistical apparatus [χ 2 (chi-squared) test and analysis of variance (ANOVA) test] in some cases. Results: The young patients were slightly more frequently boys, of all ages but with a mean age of 10 and half years. The affected LNs belonged most often to neck region, either on the left or on the right side but sometimes bilateral or even on the midline; usually, more than one LN was involved in the area. In most of the cases, the lesions were localized in only one LN area. HP picture was dominated by the inflammatory processes, firstly the nonspecific ones, followed by tuberculosis. Discussions: Our observations fitted, for each parameter, with the wide ranges found in the literature. Comparisons between parameters' variations revealed differences, sometimes significant that we tried to organize in clinical and morphological profiles. Conclusions: The assessment of our data allowed us to define some clinical and morphological profiles of different types of adenopathy that, by improvement on studies including larger series, could be of real use in daily pediatric practice.

Research in recent years on a possible and evident pathology, appeared in children s case from pregnancies obtained through in vitro fertilization (IVF), did not show significant differences than the children born from pregnancies obtained naturally. Having a good start in life, the consignments studied were feed exclusively in a natural way in the first 6 months, knowing the complex role of breast milk, including nerve growth. The delay in language development has shown significant differences between the IVF consignment and the control group and the pathology exam a possible involvement in cerebral embryogenesis, especially the Broca s area, of some disturbing factors, with a maximum of action before the 23rd week.

The medicine of the last years is evidence-based - most of the theoretical information that has occurred in the past 10 years is already out of date.The Axioma of Classical Pediatrics - Any Group A Haemolytic Beta Streptococcus must be treated with Penicillin G is no longer relevant The results of a study at the Hospital Philanthropy from Craiova are not at all surprising, overlapped with those found in medical practice.Age entails moving the diagnosis to the baby, sensitivity to penicillin occurs in only � of children, microbial resistance to the antibiotic is common in many antibiotics.

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