No abstract

Physical growth retardation is an early and prominent feature of zinc deficiency, but the effect of zinc supplementation in children is still not completely clear. This study investigated the impact of zinc supplementation on linear growth, growth velocity, IGF-I levels, and skeletal maturation of short children during and after mineral supplementation. The study was designed as a double-blind, randomized, controlled trial of zinc supplementation during a 6-month period, with a subsequent 6-month follow-up. Anthropometric data were collected at 0, 6, and 12 months. Measurements included plasma Zn, IGF-I, height, weight, triceps skinfold thickness, and body mass index. Eighteen healthy pre-pubertal short children (z-score -2.0) 7 to 10 years old with normal GH and IGF-I levels were randomized to two groups, one with zinc supplementation (5 mg/kg/d of ZnSO4) and the other with placebo. In the first 6 months, only height velocity increased significantly, 5.99+/-0.80 cm/yr vs 5.05+/-0.85 cm/yr (p=0.03). After 12 months, height velocity returned to the initial values, 3.92+/-0.59 cm/yr vs 4.19+/-1.08 cm/yr (p=0.29). This study indicates that zinc supplementation increased growth velocity, but these effects did not persist after supplementation was discontinued.

No abstract

Avaliar a prevalência de erros de prescrição de medicamentos em uma instituição de utilidade pública do Vale do Aço/Minas Gerais. Trata-se de um estudo descritivo, transversal, por meio de uma abordagem qualiquantitativa. As informações foram coletadas por meio de uma amostra de 150 prescrições de uma instituição de utilidade pública da região, na qual foram contabilizados os erros, a partir de uma análise quanto a: legibilidade, rasuras, emendas, abreviaturas, nome do medicamento, concentração, unidade de medida, forma farmacêutica, intervalo de administração, dosagem, quantidade, via de administração, tempo de tratamento e orientações sobre administração, no período de março a setembro de 2015. Detectou-se o predomínio de alguns erros, tais como: ilegibilidade, presença de rasuras, presença apenas do nome fantasia, ausência do tempo de tratamento, ausência de concentração e ausência de unidade de medida. Diante desses problemas reforça-se a importância do seguimento de prescrições padronizadas, a fim de aumentar a adesão ao tratamento e, assim, reduzir ocorrências relacionadas aos erros destas, fato que pode ser aprimorado pelo diálogo interdisciplinar.Palavras-chave: Erros de Medicação. Ilegibilidade. Interdisciplinariedade.AbstractTo evaluate the prevalence of prescription drug errors in a public utility institution Valley Steel / Minas Gerais. This was a descriptive cross-sectional study, by means of a quali-quantitative approach. Since the information was collected through a sample of 150 prescriptions of a public utility institution in the region in which the errors were recorded, from an analysis as to: Readability, erasures, amendments, abbreviations, drug name, concentration measured unit dosage form, dosing interval, dosage, quantity, route of administration, duration of treatment and administration of guidelines. We detected the predominance of some errors, such as illegibility, presence of erasures, only the presence of fancy name, absence of treatment time, lack of concentration and lack of measurement unit. In view of these problems reinforces the importance of following standard requirements in order to increase adherence to treatment and thus reduce incidents related to these errors, which can be enhanced by interdisciplinary dialogue.Keywords: Medication Errors. Illegibility. Interdisplinariedade.