The safety and efficacy of 27-G PPV for rhegmatogenous retinal detachment appear similar to 25-GPPV. We found no anatomical or functional difference in terms of postoperative BCVA, IOP, complications, and operating time. Twenty-seven-G vitrectomy is therefore a valid option in the treatment of rhegmatogenous retinal detachment.

A and B scan echography does not allow to measure separately the tickness of the three ocular layers, retina, choroid and sclera. This, however, is possible by radiofrequency signals. 48 eyes of normal subjects and 21 eyes of patient suffering from chronic glaucoma with ocular hypertension from 30 to 45 mm Hg were examined. The tickness of the retina and sclera was equal in the two groups, whereas the thickness of the choroid in the glaucomatous eyes showed an increase of 20% as compared with normal eyes.

Objective To assess the presence of retinal vascular network abnormalities in amnestic mild cognitive impairment (aMCI) patients and healthy subjects (HS) through optical coherence tomography angiography (OCTA). Methods OCTA and SD-OCT were performed in aMCI patients and cognitive normal HS. A complete neuropsychological evaluation was performed. Differences in vessel density (VD) in each retinal vascular plexus and in foveal avascular zone (FAZ) were evaluated with linear mixed model after correction for age, sex and disease duration. Results Twenty-seven aMCI patients (10 Single domain aMCI, 17 Multidomain aMCI) and 29 HS were enrolled. aMCI patients showed a statistically significant reduced VD in superficial capillary plexus (SCP), deep capillary plexus (DCP) and an increased FAZ compared to controls. When aMCI patients were divided in single domain (SD) and multiple domains (MD) aMCI, SD aMCI showed no VD differences in SCP, DCP and Radial Peripapillary Capillary, while the FAZ area was significantly larger compared to controls. In MD aMCI, VD values were lower and FAZ was increased compared to controls. Comparing both aMCI groups, MD aMCI showed a significant reduction in VD values of SCP. No correlation was found between mini mental state examination (MMSE) scores and OCTA parameters. Conclusions OCTA is able to detect changes in retinal microvascular network in early cognitive deficits and, the most sensitive alteration seems to be the enlargement of the FAZ. This non-invasive tool provides useful information on retinal involvement patterns in MCI diagnosis and

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OCT angiography can be considered a reliable, easy-to-perform method with which to evaluate microvascular changes of optic nerve head for the early diagnosis and follow-up of glaucoma.