An innovative protocol to the synthesis of this material emerged on exploring the potential of the various form of N-aminophthalimides on its reaction with a number of aromatic aldehydes. New series of biologically active substituted Schiff bases with general formula, R1N=CHR2 where R1 = 3-nitro-N-aminophthalimide, 3-bromo-N-aminophthalimide, 4-nitro-N-aminophthalimide, 4-bromo-N-aminophthalimide, R2 =2, 6-dichlorobenzaldehyde, o-anisaldehyde and o-vanillin were synthesized by the reaction of substituted N-aminophthalimides and substituted aldehydes in ethanol. Moreover N-aminophthalimides (50-70% yield) were synthesized by reactions of corresponding phthalimides and hydrazine hydrate. Such compounds were characterized by different physico-chemical techniques like, melting point, elemental analysis, multinuclear NMR (1H, 13C).The synthesized compounds were screened for antibacterial and antifungal activities. The explorations of the biological properties of the compounds are mentioned in this paper.

INTRODUCTIONThe triazoles are of great biological [1][2][3][4][5][6] significance. It is also powerful fungicide. The present communication reports the results of the spectro-photometric studies of the complexes of Pb(II) with 5-mercapto-4-amino-3-methyl 1, 2, 4 Triazole prepared 7-9 . Isolation of the ComplexesA mixture of hot aqueous solution of lead acetate and ligand were taken in the ratio of 1:2. By adding NaOH the pH of the mixture 4, 7 and 11 adjusted. The mixtures were refluxed till complexes were precipitated. The complexes obtained were further treated with ethanolic solution, then ether, then were filtered by suction, washed with ethanol and ether, dried at 100°C in the electric oven for several hours. ORIENTAL JOURNAL OF CHEMISTRYwww.orientjchem.org Est. 1984 An ABSTRACTThe Pb(II) with 5-mercapto-4-Amino-3-methyl, 1, 2, 4, triazole complexes has been prepared. The Structural assessments of the complexes have been made on the basis of result of IR Studies.

No abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.