Kulit buah manggis (Garcinia mangostana Linn.) mengandung senyawa xanton yang diketahui memiliki aktivitas antioksidan yang tinggi. Penelitian sebelumnya menunjukkan bahwa Fraksi Etil Asetat Kulit Buah Manggis (FEAKBM) memiliki aktivitas antioksidan paling tinggi dibandingkan fraksi air dan n-heksan. Penelitian ini bertujuan untuk membuat formulasi dan mengarakterisasi sediaan masker gel peel-off mengandung FEAKBM. Masker gel peel-off diformulasi menggunakan Polivinil Alkohol (PVA) dan Hidroksi Propil Metil Selulosa (HPMC) sebagai gelling agent. Uji aktivitas antioksidan dari fraksi dan sediaan dilakukan secara in-vitro dengan uji peredaman DPPH. Terhadap sediaan dilakukan evaluasi pH, viskositas, daya sebar, dan waktu mengering. Fraksi etil asetat kulit buah manggis memiliki aktivitas antioksidan sangat tinggi dengan nilai IC 50 19,240 µg/mL. Formula optimum basis masker gel mengandung PVA 14% dan HPMC 1%. Sediaan masker gel peel-off stabil berdasarkan uji stabilitas fisik pada suhu 40 o C selama 28 hari penyimpanan. Sediaan masker gel peel-off mengandung FEAKBM 1% memiliki aktivitas antioksidan dengan nilai persen inhibisi 53,57±0,591.
The main problems found in the Malaya Farmer Group in Pasirjambu District which are partners, are problems related to honey bee harvesting techniques and the diversification of honey products. Some of the methods applied to achieve the target are coordination with domestic and foreign partners through outreach, discussions, identification of problem solutions, selection of alternative solutions to problems, and formulation of implementation stages. Then the implementation of training on honey bee harvesting techniques, the practice of making diversified honey products, and marketing the results of diversified honey products. The achievement of this community service has obtained data in the form of honey product diversification including Honey Combination Soap, Honey Ginger Candy, and Honey Milk Coffee Drinks with the MAZALI brand. In addition, through this community service, training on honey bee harvesting techniques was successfully carried out with the title Trigona Honey Bee Cultivation Training with the theme of Harvesting Techniques, Quality Assessment, and Diversification of Trigona Honey Products. It is hoped that this community service can provide benefits for the development of science, especially in order to help improve skills in honey bee harvesting techniques and develop various diversifications of honey products so that they can become superior in Pasirjambu District.
Green tea (Camellia sinensis L.) is known to have activity as antioxidant and sunscreen due to its catechin compound. The major catechin-derived compound is epigallocatechin gallate (EGCG). However, EGCG in green tea leaves is unstable due to its rapid degradation and large molecular mass of 458 daltons, making it difficult to penetrate the skin. The purpose of this research is to formulate solid lipid nanoparticles (SLN) of green tea leaves ethanol extract using high speed homogenization and sonication method, as well as to evaluate SLN ability in improving extract stability as sunscreen using UV-Vis spectrophotometry. SLN formula contained 0,1% green tea leaves ethanol extract, and the most optimal formula was composed of 4% lipid (Precirol ATO 5:Gelucire 44/14) 4:1 and 1% Kolliphor P188 as surfactant. Characterization results showed particle size of 286.7 nm, polydispersity index 0.296, and zeta potential -3.7 mV. Photostability test using 120-minutes irradiation showed decrease in percentage of DPPH free radicals damping at 5.34% extract and 1.77% SLN for UVA, and 7.7% extract and 2.34% SLN for UVB.
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