4.

Rhabdomyoma is an uncommon benign mesenchymal tumor with skeletal muscle differentiation that may occur either in the heart or in extracardiac sites. Even though the head and neck region is the most common area of extracardiac rhabdomyoma, the larynx is rarely involved. We present the case of an 85-year-old woman who reported a 10-day history of breathing difficulties, dysphagia, and dysphonia. A computed tomography scan of the head and neck showed a contrast-enhanced, solid hypopharyngeal-laryngeal neoplasm with well-defined margins causing subtotal obliteration of the right pyriform sinus and a reduction in air lumen of the laryngeal vestibule. The patient underwent complete endoscopic removal of the lesion; histologic examination revealed an adult-type rhabdomyoma based on the histologic features and the immunoreactivity of the neoplastic cells for desmin, myoglobin, and muscle-specific actin but not for cytokeratin, S-100, CD68R, chromogranin-A, and synaptophysin. Since clinical and imaging features are not specific for rhabdomyoma, histologic examination and immunohistochemical analyses play a central role in the differential diagnosis of the adult-type rhabdomyoma from other laryngeal neoplasms. A correct diagnosis is mandatory to avoid inappropriate treatment.

Background: Total thyroidectomy (TT) and completion thyroidectomy (CT) are two common surgical operations that are frequently followed by vocal symptoms despite preservation of the recurrent laryngeal nerve (RLN) and of the external branch of superior laryngeal nerve (EBSLN). The aim of this study was to analyze vocal alterations through endoscopic findings, videolaryngostroboscopy (VLS), acoustic vocal parameters and impact on patients’ quality of life after surgery in the absence of laryngeal nerve injury. Methods: We enrolled 198 patients who underwent thyroidectomy by the same surgeon. One hundred twenty-six patients underwent TT (group TT) while 72 underwent CT (group CT). All patients underwent preoperative VLS and Voice Handicap Index (VHI) assessment and postoperative VHI, VLS and Acoustic Voice Analysis with Multidimensional Voice Program Analysis 12 to 18 months after surgery. Results: We observed a statistically significant higher rate of EBSLN injury in CT compared to TT. Even in the absence of RLN and EBSLN injury, patients who underwent TT and CT presented slightly worse acoustic vocal parameters and VHI scores compared to healthy controls. Interestingly, some acoustic vocal parameters and VHI scores were significantly worse in group CT compared to group TT. Conclusions: The higher rate of EBSLN injury in CT rather than in TT suggests a higher surgical risk in CT. The vocal parameters of loudness and self-perception of voice were significantly worse after CT, suggesting a larger trauma in patients’ vocal outcome in CT if compared to TT, although these alterations were not reported as psychologically limiting daily life of patients. Nevertheless, the existence of multiple factors contributing to vocal alterations after thyroidectomy highlight the importance of a routine comprehensive functional voice analysis before and after surgery.

Objectives Otosclerosis is a progressive disease of the otic capsule characterised by disordered bone remodelling with abnormal resorption and neoformation of the temporal bone. Fenestral (or stapedial) otosclerosis is the most frequent form, when the focus of demineralisation involves the stapes footplate and the oval window. Stapedotomy and stapedectomy are indisputably the two main stapes surgery techniques for otosclerosis. The aims of this article are to evaluate the outcome of stapedotomy in terms of long-term audiological results and possible onset of late audiovestibular complications. Methods This retrospective study included 63 patients who underwent primary stapedotomy for treatment of conductive hearing loss due to otosclerosis with more than 15 years postoperative follow-up. Results We compared the preoperative results with the long-term stapedotomy results and observed an improvement of the pure tone average (PTA) for air conduction (AC) of 10.6 ± 7.6 dB and an average air/bone gap (ABG) improvement of 22.6 ± 5.7 dB. A surgical revision was necessary in two cases (3%). Complications included tinnitus in 5 cases and a temporary hypogeusia in two patients (3%); in the immediate postoperative period, 6 patients (10.2%) complained of vertigo. Conclusions Our results provide further evidence of the validity of stapedotomy as the reference technique for the surgical treatment of fenestral otosclerosis.